Table 3 Estimates of the fixed and random parts of the models with interaction of the baseline grouping with ADAM10, and random effect on the intercept, using MMSE score values on follow-up as the dependent variable
From: ADAM10 plasma levels predict worsening in cognition of older adults: a 3-year follow-up study
| Model 4 | Model 5 | |||||
|---|---|---|---|---|---|---|
| Fixed effects | Estimate | SE | p | Estimate | SE | p |
| Intercept | 1.72 | 0.82 | 0.03 | 10.93 | 1.60 | < 0.001 |
| Age, years | – | – | – | − 0.11 | 0.01 | < 0.001 |
| Male sex | – | – | – | 0.17 | 0.25 | 0.4 |
| Altered MMSE: ADAM10 (ng/mL) | − 0.08 | 0.1 | 0.4 | − 0.1 | 0.1 | 0.2 |
| Normal MMSE: ADAM10 (ng/mL) | − 0.2 | 0.08 | 0.001 | − 0.2 | 0.08 | 0.001 |
| Baseline MMSE score | 0.93 | 0.03 | < 0.001 | 0.88 | 0.03 | < 0.001 |
| Random effects | Variance | SD | Variance | SD | ||
| Individuals (intercept) | 0.0 | 0.0 | 0.0 | 0.0 | ||
| Residuals | 6.64 | 2.58 | 6.0 | 2.45 | ||
| Bayesian information criterion | 1944 | 1921 | ||||