ADAM10 plasma levels predict worsening in cognition of older adults: a 3-year follow-up study

Table 4 Results for the multivariate linear regression model using baseline and follow-up MMSE scores as the dependent variable

Baseline
Dependent variable	R²	Adjusted R²	p
MMSE baseline score	0.47	0.46	< 0.001
Baseline independent variables	Unstandardized β coefficient	SE
Intercept	30.79	2.27	< 0.001
Age, years	−0.09	0.03	0.003
Male sex	0.81	0.45	0.07
Altered MMSE	−6.02	0.48	< 0.001
ADAM10, ng/mL	−0.1	0.2	0.4
Follow-up
Dependent variable	R²	Adjusted R²	p
MMSE follow-up score	0.54	0.53	< 0.001
Follow-up independent variables	Unstandardized β coefficient	SE
Intercept	38.97	2.63	< 0.001
Age, years	− 0.20	0.03	< 0.001
Male sex	1.52	0.49	0.002
Altered MMSE	− 6.12	0.52	< 0.001
ADAM10, ng/mL	− 0.2	0.1	0.06

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