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Table 2 Demographics, PMI, and clinical diagnosis for AD-DS and C/AD-DS frontal cortex samples

From: Normal levels of KIF5 but reduced KLC1 levels in both Alzheimer disease and Alzheimer disease in Down syndrome: evidence suggesting defects in anterograde transport

Patient Gender Age (years) Post-mortem interval (h) Diagnosis
C/AD-DS 1* Female 95 2.5 Cognitively normal
C/AD-DS 2* Male 93 3 Cognitively normal
C/AD-DS 3* Male 79 3 Cognitively normal
C/AD-DS 4 Male 74 3.3 Cognitively normal
C/AD-DS 5* Female 58 3.1 Cognitively normal
C/AD-DS 6* Female 49 7 Cognitively normal
C/AD-DS 7* Female 54 6 Cognitively normal
C/AD-DS 8* Female 59 5.9 Cognitively normal
C/AD-DS 9* Male 48 6 Cognitively normal
C/AD-DS 10* Male 57 16 Cognitively normal
C/AD-DS 11* Male 58 9 Cognitively normal
C/AD-DS 12 Female 50 7 Cognitively normal
C/AD-DS 13 Female 46 18 Cognitively normal
C/AD-DS 14 Female 39 19 Cognitively normal
C/AD-DS 15 Male 59 5.9 Cognitively normal
C/AD-DS 16 Male 59 15.8 Cognitively normal
C/AD-DS 17 Female 48 8 Cognitively normal
C/AD-DS 18 Female 51 21 Cognitively normal
C/AD-DS 19 Female 57 7 Cognitively normal
Mean ± SEM 11F/8M 60 ± 3 8.8 ± 1.4  
AD-DS 1 Female 45 2.7 Trisomy 21 with AD
AD-DS 2 Male 46 6.4 Trisomy 21 with AD
AD-DS 3 Male 49 2.2 Trisomy 21 with AD
AD-DS 4 Male 55 4.5 Trisomy 21 with AD
AD-DS 5 Female 57 6 Trisomy 21 with AD
AD-DS 6 Female 46 7 Trisomy 21 with AD
AD-DS 7 Male 65 10 Trisomy 21 with AD
AD-DS 8 Male 56 16 Trisomy 21 with AD
AD-DS 9 Male 55 12 Trisomy 21 with AD
AD-DS 10 Male 57 5 Trisomy 21 with AD
AD-DS 11 Female 51 4 Trisomy 21 with AD
AD-DS 12 Male 57 3 Trisomy 21 with AD
AD-DS 13 Male 41 15 Trisomy 21 with AD
AD-DS 14 Male 64 20 Trisomy 21 with AD
AD-DS 15 Male 51 15.7 Trisomy 21 with AD
AD-DS 16 Male 50 22.8 Trisomy 21 with AD
AD-DS 17 Female 45 2.75 Trisomy 21 with AD
AD-DS 18 Female 47 6.5 Trisomy 21 with AD
AD-DS 19 Female 50 5 Trisomy 21 with AD
AD-DS 20 Female 52 4.37 Trisomy 21 with AD
AD-DS 21 Female 62 2.42 Trisomy 21 with AD
Mean ± SEM 9F/12M 52 ± 1 8.3 ± 1.4  
  1. *The control samples also listed as C/AD in Table 1; these samples together with the remaining controls constituted the samples designated as C/COMB
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Alzheimer's Research & Therapy

ISSN: 1758-9193

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