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Characteristic
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No. (n = 1108)
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Age (years)
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61.1 ± 11.0 (41 to 89)
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Sex (F/M)
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461/647
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Education (years)
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9.8 ± 4.4
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CM-MMSE
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28.2 ± 1.9
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MoCA
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23.8 ± 4.0
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*APOE ε4 (carriers/non-carriers)
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161/800
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*CSF Aβ42 (pg/ml)
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167.6 ± 79.5
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*CSF Aβ40 (pg/ml)
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5981.8 ± 2728.5
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*CSF tau (pg/ml)
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171.3 ± 76.1
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*CSF p-tau (pg/ml)
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36.8 ± 9.1
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Healthy lifestyle factors (n, %)
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No current smoking
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888 (80.1%)
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No or moderate drinking
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951 (85.8%)
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Regular physical activity
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275 (24.8%)
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Absence of social isolation
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868 (78.3%)
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No. of healthy lifestyle factors (n, %)
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0
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9 (0.8%)
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1
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84 (7.6%)
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2
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302 (27.3%)
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3
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558 (50.4%)
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4
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155 (14.0%)
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- Summarized as mean ± standard deviation (SD) for continuous data and count for categorical data. Abbreviations: CSF, cerebrospinal fluid; MMSE, Mini-Mental State Examination; p-tau, phosphorylated tau
- * Data were missing for CSF Aβ42 (n = 162, 14.6%), CSF Aβ40 (n = 198, 17.9%), CSF tau (n = 92, 8.3%), CSF p-tau (n = 90, 8.1%), and APOE ε4 statues (n = 147, 13.3%)